fabrication of biopolymer platforms for nutraceutical delivery

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Joyce Boye I. Nutraceutical and Functional Food Processing Technology Joyce Boye I. Nutraceutical and Functional Food Processing Technology
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Joyce Boye I. Nutraceutical and Functional Food Processing Technology


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15444.46 руб.

For several years, the food industry has been interested in identifying components in foods which have health benefits to be used in the development of functional food and nutraceutical products. Examples of these ingredients include fibre, phytosterols, peptides, proteins, isoflavones, saponins, phytic acid, probiotics, prebiotics and functional enzymes. Although much progress has been made in the identification, extraction and characterisation of these ingredients, there remains a need for ready and near-market platform technologies for processing these ingredients into marketable value-added functional food and nutraceutical products. This book looks at how these ingredients can be effectively incorporated into food systems for market, and provides practical guidelines on how challenges in specific food sectors (such as health claims and marketing) can be addressed during processing. Nutraceutical and Functional Food Processing Technology is a comprehensive overview of current and emerging trends in the formulation and manufacture of nutraceutical and functional food products. It highlights the distinctions between foods falling into the nutraceutical and functional food categories. Topics include sustainable and environmentally–friendly approaches to the production of health foods, guidelines and regulations, and methods for assessing safety and quality of nutraceutical and functional food products. Specific applications of nutraceuticals in emulsion and salad dressing food products, beverages and soft drinks, baked goods, cereals and extruded products, fermented food products are covered, as are novel food proteins and peptides, and methods for encapsulated nutraceutical ingredients and packaging. The impact of processing on the bioactivity of nutraceutical ingredients, allergen management and the processing of allergen-free foods, health claims and nutraceutical food product commercialization are also discussed. Nutraceutical and Functional Food Processing Technology is a comprehensive source of practical approaches that can be used to innovate in the nutraceutical and health food sectors. Fully up-to-date and relevant across various food sectors, the book will benefit both academia and industry personnel working in the health food and food processing sectors.

Tayyab Suratwala I. Materials Science and Technology of Optical Fabrication Tayyab Suratwala I. Materials Science and Technology of Optical Fabrication
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Tayyab Suratwala I. Materials Science and Technology of Optical Fabrication


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9723.89 руб.

Covers the fundamental science of grinding and polishing by examining the chemical and mechanical interactions over many scale lengths Manufacturing next generation optics has been, and will continue to be, enablers for enhancing the performance of advanced laser, imaging, and spectroscopy systems. This book reexamines the age-old field of optical fabrication from a materials-science perspective, specifically the multiple, complex interactions between the workpiece (optic), slurry, and lap. It also describes novel characterization and fabrication techniques to improve and better understand the optical fabrication process, ultimately leading to higher quality optics with higher yield. Materials Science and Technology of Optical Fabrication is divided into two major parts. The first part describes the phenomena and corresponding process parameters affecting both the grinding and polishing processes during optical fabrication. It then relates them to the critical resulting properties of the optic (surface quality, surface figure, surface roughness, and material removal rate). The second part of the book covers a number of related topics including: developed forensic tools used to increase yield of optics with respect to surface quality (scratch/dig) and fracture loss; novel characterization and fabrication techniques used to understand/quantify the fundamental phenomena described in the first part of the book; novel and recent optical fabrication processes and their connection with the fundamental interactions; and finally, special techniques utilized to fabricate optics with high damage resistance. Focuses on the fundamentals of grinding and polishing, from a materials science viewpoint, by studying the chemical and mechanical interactions/phenomena over many scale lengths between the workpiece, slurry, and lap Explains how these phenomena affect the major characteristics of the optic workpiece—namely surface figure, surface quality, surface roughness, and material removal rate Describes methods to improve the major characteristics of the workpiece as well as improve process yield, such as through fractography and scratch forensics Covers novel characterization and fabrication techniques used to understand and quantify the fundamental phenomena of various aspects of the workpiece or fabrication process Details novel and recent optical fabrication processes and their connection with the fundamental interactions Materials Science and Technology of Optical Fabrication is an excellent guidebook for process engineers, fabrication engineers, manufacturing engineers, optical scientists, and opticians in the optical fabrication industry. It will also be helpful for students studying material science and applied optics/photonics.

Sabu Thomas Biopolymer Nanocomposites. Processing, Properties, and Applications Sabu Thomas Biopolymer Nanocomposites. Processing, Properties, and Applications
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Sabu Thomas Biopolymer Nanocomposites. Processing, Properties, and Applications


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14772.84 руб.

Sets forth the techniques needed to create a vast array of useful biopolymer nanocomposites Interest in biopolymer nanocomposites is soaring. Not only are they green and sustainable materials, they can also be used to develop a broad range of useful products with special properties, from therapeutics to coatings to packaging materials. With contributions from an international team of leading nanoscientists and materials researchers, this book draws together and reviews the most recent developments and techniques in biopolymer nano-composites. It describes the preparation, processing, properties, and applications of bio- polymer nanocomposites developed from chitin, starch, and cellulose, three renewable resources. Biopolymer Nanocomposites features a logical organization and approach that make it easy for readers to take full advantage of the latest science and technology in designing these materials and developing new products and applications. It begins with a chapter reviewing our current understanding of bionanocomposites. Next, the book covers such topics as: Morphological and thermal investigations of chitin-based nanocomposites Applications of starch nanoparticle and starch-based bionanocomposites Spectroscopic characterization of renewable nanoparticles and their composites Nanocellulosic products and their applications Protein-based nanocomposites for food packaging Throughout the book, detailed case studies of industrial applications underscore the unique challenges and opportunities in developing and working with biopolymer nanocomposites. There are also plenty of figures to help readers fully grasp key concepts and techniques. Exploring the full range of applications, Biopolymer Nanocomposites is recommended for researchers in a broad range of industries and disciplines, including biomedical engineering, materials science, physical chemistry, chemical engineering, and polymer science. All readers will learn how to create green, sustainable products and applications using these tremendously versatile materials.

Kun Cheng Advanced Drug Delivery Kun Cheng Advanced Drug Delivery
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Kun Cheng Advanced Drug Delivery


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9673.78 руб.

Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

Li Chun Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action Li Chun Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action
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Li Chun Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action


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13691.23 руб.

Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important tool for the development of new drug delivery systems, shedding new light on the pharmacokinetics, biodistribution, bioavailability, local concentration, and clearance of drug substances for the treatment of human disease, most notably cancer. Written by a team of international experts, this book examines the use of quantitative imaging techniques in designing and evaluating novel drug delivery systems and applications. Drug Delivery Applications of Noninvasive Imaging offers a full arsenal of tested and proven methods, practices and guidance, enabling readers to overcome the many challenges in creating successful new drug delivery systems. The book begins with an introduction to molecular imaging. Next, it covers: In vivo imaging techniques and quantitative analysis Imaging drugs and drug carriers at the site of action, including low-molecular weight radiopharmaceuticals, peptides and proteins, siRNA, cells, and nanoparticles Applications of imaging techniques in administration routes other than intravenous injection, such as pulmonary and oral delivery Translational research leading to clinical applications Imaging drug delivery in large animal models Clinical applications of imaging techniques to guide drug development and drug delivery Chapters are based on a thorough review of the current literature as well as the authors' firsthand experience working with imaging techniques for the development of novel drug delivery systems. Presenting state-of-the-technology applications of imaging in preclinical and clinical evaluation of drug delivery systems, Drug Delivery Applications of Noninvasive Imaging offers cost-effective strategies to pharmaceutical researchers and students for developing drug delivery systems that accurately target a broad range of disease conditions.

Rebecca Bader A. Engineering Polymer Systems for Improved Drug Delivery Rebecca Bader A. Engineering Polymer Systems for Improved Drug Delivery
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Rebecca Bader A. Engineering Polymer Systems for Improved Drug Delivery


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9973.3 руб.

Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi
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Cheng Kun Advanced Delivery and Therapeutic Applications of RNAi


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16098.86 руб.

RNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic acid-based therapies, RNAi has great potential in treating various life-threatening diseases. However, the poor stability and cellular uptake of RNAi molecules remain considerable barriers to their efficient delivery which is paramount to a successful therapy. This book provides a comprehensive introduction to RNAi delivery, then goes on to discuss different delivery strategies, and concludes with current applications in various diseases. It covers: Mechanisms, Barriers, and Analysis of RNAi Delivery Nonclinical Safety Assessments and Clinical Pharmacokinetics: A Regulatory Perspective Bioconjugation of siRNA for Site Specifi c Delivery Nanoscale Delivery Systems for RNAi Environmentally-Responsive Delivery Systems for RNAi Light-sensitive RNAi Viral-Mediated Delivery of shRNA and miRNA RNAi applications in Cancer Therapy, Liver Diseases, Hepatitis B, and Ocular Disease miRNA as therapeutic agents and targets Advanced Delivery and Therapeutic Applications of RNAi combines the essential aspects of developing RNAi therapeutics from bench to clinic, and is invaluable for researchers working on RNAi, drug discovery and delivery, biomedical engineering, biomaterials, molecular biology, and biotechnology.

Jorge Carlos Ruiz Ruiz New Polymers for Encapsulation of Nutraceutical Compounds Jorge Carlos Ruiz Ruiz New Polymers for Encapsulation of Nutraceutical Compounds
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Jorge Carlos Ruiz Ruiz New Polymers for Encapsulation of Nutraceutical Compounds


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13318.61 руб.

The incorporation of functional ingredients in a given food system and the processing and handling of such foods are associated with nutritional challenges for their healthy delivery. The extreme sensitivity of some components cause significant loss of product quality, stability, nutritional value and bioavailability, and the overall acceptability of the food product. Consequently, encapsulation has been successfully used to improve stability and bioavailability of functional ingredients. Encapsulation is one example of technology that has the potential to meet the challenge of successfully incorporating and delivering functional ingredients into a range of food types. The book will cover topics about 1) Characterization of novel polymers and their use in encapsulation processes. 2) Stability of nutraceutical compounds encapsulated with novel polymers. 3) Application of encapsulated compounds with novel polymers in functional food systems. This book provides a detailed overview of technologies for preparing and characterisation of encapsulates for food active ingredients using modified polymers. The use of modified polymers as coating materials it is a field that still needs study. The book is aimed to inform students and researchers in the areas of food science and food technology, and professionals in the food industry.

Joseph T. DiBene, II Fundamentals of Power Integrity for Computer Platforms and Systems Joseph T. DiBene, II Fundamentals of Power Integrity for Computer Platforms and Systems
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Joseph T. DiBene, II Fundamentals of Power Integrity for Computer Platforms and Systems


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10048.72 руб.

An all-encompassing text that focuses on the fundamentals of power integrity Power integrity is the study of power distribution from the source to the load and the system level issues that can occur across it. For computer systems, these issues can range from inside the silicon to across the board and may egress into other parts of the platform, including thermal, EMI, and mechanical. With a focus on computer systems and silicon level power delivery, this book sheds light on the fundamentals of power integrity, utilizing the author’s extensive background in the power integrity industry and unique experience in silicon power architecture, design, and development. Aimed at engineers interested in learning the essential and advanced topics of the field, this book offers important chapter coverage of fundamentals in power distribution, power integrity analysis basics, system-level power integrity considerations, power conversion in computer systems, chip-level power, and more. Fundamentals of Power Integrity for Computer Platforms and Systems: Introduces readers to both the field of power integrity and to platform power conversion Provides a unique focus on computer systems and silicon level power delivery unavailable elsewhere Offers detailed analysis of common problems in the industry Reviews electromagnetic field and circuit representation Includes a detailed bibliography of references at the end of each chapter Works out multiple example problems within each chapter Including additional appendixes of tables and formulas, Fundamentals of Power Integrity for Computer Platforms and Systems is an ideal introductory text for engineers of power integrity as well as those in the chip design industry, specifically physical design and packaging.

Zhongwei Gu Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery Zhongwei Gu Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery
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Zhongwei Gu Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery


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13497.9 руб.

Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid systems on the nanoscale, with a focus on their adaptability for different cargoes and target tissues. Thanks to the broad coverage of carriers as well as cargoes discussed, every researcher in the field will find valuable information here.

Ryan Donnelly F. Microneedle-mediated Transdermal and Intradermal Drug Delivery Ryan Donnelly F. Microneedle-mediated Transdermal and Intradermal Drug Delivery
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Ryan Donnelly F. Microneedle-mediated Transdermal and Intradermal Drug Delivery


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11619.63 руб.

Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.

Yoon Yeo Nanoparticulate Drug Delivery Systems. Strategies, Technologies, and Applications Yoon Yeo Nanoparticulate Drug Delivery Systems. Strategies, Technologies, and Applications
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Yoon Yeo Nanoparticulate Drug Delivery Systems. Strategies, Technologies, and Applications


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11998.84 руб.

Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.

Sabu Thomas Handbook of Biopolymer-Based Materials. From Blends and Composites to Gels and Complex Networks Sabu Thomas Handbook of Biopolymer-Based Materials. From Blends and Composites to Gels and Complex Networks
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Sabu Thomas Handbook of Biopolymer-Based Materials. From Blends and Composites to Gels and Complex Networks


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28271.44 руб.

This first systematic scientific reference in the area of micro- and nanostructured biopolymer systems discusses in two volumes the morphology, structure, dynamics, properties and applications of all important biopolymers, as well as their blends, composites, interpenetrating networks and gels. Selected leading researchers from industry, academia, government and private research institutions around the globe comprehensively review recent accomplishments in the field. They examine the current state of the art, new challenges, and opportunities, discussing all the synthetic routes to the generation of both micro- and nano-morphologies, as well as the synthesis, characterization and application of porous biopolymers. An outstanding resource for anyone involved in the fi eld of eco-friendly biomaterials for advanced technologies.

Ryan Donnelly F. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery Ryan Donnelly F. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery
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Ryan Donnelly F. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery


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10873.3 руб.

This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.

Juergen Siepmann Computational Pharmaceutics. Application of Molecular Modeling in Drug Delivery Juergen Siepmann Computational Pharmaceutics. Application of Molecular Modeling in Drug Delivery
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Juergen Siepmann Computational Pharmaceutics. Application of Molecular Modeling in Drug Delivery


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11998.84 руб.

Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.

Vijay Thakur Kumar Handbook of Composites from Renewable Materials, Nanocomposites. Advanced Applications Vijay Thakur Kumar Handbook of Composites from Renewable Materials, Nanocomposites. Advanced Applications
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Vijay Thakur Kumar Handbook of Composites from Renewable Materials, Nanocomposites. Advanced Applications


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20622.5 руб.

The Handbook of Composites From Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The handbook covers a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Together, the 8 volumes total at least 5000 pages and offers a unique publication. This 8th volume of the Handbook is solely focused on the Nanocomposites: Advanced Applications. Some of the important topics include but not limited to: virgin and recycled polymers applied to advanced nanocomposites; biodegradable polymer-carbon nanotube composites for water and wastewater treatment; eco-friendly nanocomposites of chitosan with natural extracts, antimicrobial agents and nanometals; controllable generation of renewable nanofibrils from green materials and their application in nanocomposites; nanocellulose and nanocellulose composites; poly (lactic acid) biopolymer composites and nanocomposites for biomedical and biopackaging applications; impact of nanotechnology in water treatment: carbon nanotube and graphene; nanomaterials in energy generation; sustainable green nanocomposites from bacterial bioplastics for food packaging applications; PLA-nanocomposites: a promising material for future from renewable resources; bio-composites from renewable resources: preparation and applications of chitosan-clay nanocomposites; nano materials: an advanced and versatile nano additive for kraft and paper industries; composites and nanocomposites based on polylactic acid obtaining; cellulose-containing scaffolds fabricated by electrospinning: applications in tissue engineering and drug delivery; biopolymer-based nanocomposites for environmental applications; calcium phosphate nanocomposites for biomedical and dental applications: recent developments; chitosan-metal nanocomposites: synthesis, characterization and applications; multi-carboxyl functionalized nano-cellulose/nano-bentonite composite for the effective removal and recovery of metal ions; biomimetic gelatin nanocomposite as a scaffold for bone tissue repair; natural starches-blended ionotropically-gelled microparticles/beads for sustained drug release and ferrogels: smart materials for biomedical and remediation applications.

Kwok Chow Therapeutic Delivery Solutions Kwok Chow Therapeutic Delivery Solutions
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Kwok Chow Therapeutic Delivery Solutions


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9673.78 руб.

Provides a comprehensive review of all types of medical therapeutic delivery solutions from traditional pharmaceutical therapy development to innovative medical device therapy treatment to the recent advances in cellular and stem cell therapy development • Provides information to potentially allow future development of treatments with greater therapeutic potential and creativity • Includes associated regulatory requirements for the development of these therapies • Provides a comprehensive developmental overview on therapeutic delivery solutions • Provides overview information for both the general reader as well as more detailed references for professionals and specialists in the field

Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery
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Nahar Chowdhury Lutfun Steroid Dimers. Chemistry and Applications in Drug Design and Delivery


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14935.89 руб.

Steroid dimers are an important group of compounds produced by various marine organisms, and also synthesized in the laboratories. This group of compounds possesses various pharmacological and biological properties, and can also be used to create “molecular umbrellas” for drug delivery. Steroid Dimers: Chemistry and Applications in Drug Design and Delivery provides an up-to-date overview on the chemistry and applications of steroid dimers of natural and synthetic origins. The book includes easy-to-follow synthetic protocols for various classes of important dimeric steroids, source details, valuable spectroscopic data and depiction of unique structural features of natural steroidal dimers, and the Structure-Activity-Relationships (SARs) of some pharmacologically active dimeric steroids. Topics covered include: introduction to steroid dimers synthesis and chemistry of noncyclic and cyclic steroid dimers naturally occurring steroid dimers – cephalostatins, ritterazines and crellastatins biological and pharmacological functions of steroid dimers and their application in drug design and discovery steroid dimers as “molecular umbrellas” for drug delivery Steroid Dimers: Chemistry and Applications in Drug Design and Delivery is an essential guide to this important class of natural and synthetic compounds for researchers and students of natural products chemistry and biochemistry, synthetic organic and medicinal chemistry, and drug design, discovery and delivery.

Laurent Simon Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering Laurent Simon Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering
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Laurent Simon Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering


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8630.92 руб.

Enables readers to apply process dynamics and control theory to solve bioprocess and drug delivery problems The control of biological and drug delivery systems is critical to the health of millions of people worldwide. As a result, researchers in systems biology and drug delivery rely on process dynamics and control theory to build our knowledge of cell behavior and to develop more effective therapeutics, controlled release devices, and drug administration protocols to manage disease. Written by a leading expert and educator in the field, this text helps readers develop a deep understanding of process dynamics and control theory in order to analyze and solve a broad range of problems in bioprocess and drug delivery systems. For example, readers will learn how stability criteria can be used to gain new insights into the regulation of biological pathways and lung mechanics. They'll also learn how the concept of a time constant is used to capture the dynamics of diffusive processes. Readers will also master such topics as external disturbances, transfer functions, and input/output models with the support of the author's clear explanations, as well as: Detailed examples from the biological sciences and novel drug delivery technologies 160 end-of-chapter problems with step-by-step solutions Demonstrations of how computational software such as MATLAB and Mathematica solve complex drug delivery problems Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering is written primarily for undergraduate chemical and biomedical engineering students; however, it is also recommended for students and researchers in pharmaceutical engineering, process control, and systems biology. All readers will gain a new perspective on process dynamics and control theory that will enable them to develop new and better technologies and therapeutics to treat human disease.

Ravi Birla Introduction to Tissue Engineering. Applications and Challenges Ravi Birla Introduction to Tissue Engineering. Applications and Challenges
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Ravi Birla Introduction to Tissue Engineering. Applications and Challenges


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10124.13 руб.

A comprehensive reference and teaching aid on tissue engineering—covering everything from the basics of regenerative medicine to more advanced and forward thinking topics such as the artificial liver, bladder, and trachea Regenerative medicine/tissue engineering is the process of replacing or regenerating human cells, tissues, or organs to restore or establish normal function. It is an incredibly progressive field of medicine that may, in the near future, help with the shortage of life-saving organs available through donation for transplantation. Introduction to Tissue Engineering: Applications and Challenges makes tissue engineering more accessible to undergraduate and graduate students alike. It provides a systematic and logical eight-step process for tissue fabrication. Specific chapters have been dedicated to provide in-depth principles for many of the supporting and enabling technologies during the tissue fabrication process and include biomaterial development and synthesis, bioreactor design, and tissue vascularization. The tissue fabrication process is further illustrated with specific examples for liver, bladder, and trachea. Section-coverage includes an overall introduction of tissue engineering; enabling and supporting technologies; clinical applications; and case studies and future challenges. Introduction to Tissue Engineering: Presents medical applications of stem cells in tissue engineering Deals with the effects of chemical stimulation (growth factors and hormones) Covers current disease pathologies and treatment options (pacemakers, prosthesis) Explains bioengineering, design and fabrication, and critical challenges during tissue fabrication Offers PowerPoint slides for instructors Features case studies and a section on future directions and challenges As pioneering individuals look ahead to the possibility of generating entire organ systems, students may turn to this text for a comprehensive understanding and preparation for the future of regenerative medicine.

Ashutosh Tiwari Advanced Surfaces for Stem Cell Research Ashutosh Tiwari Advanced Surfaces for Stem Cell Research
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Ashutosh Tiwari Advanced Surfaces for Stem Cell Research


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16873.08 руб.

The book outlines first the importance of Extra Cellular Matrix (ECM), which is a natural surface for most of cells. In the following chapters the influence of biological, chemical, mechanical, and physical properties of surfaces in micro and nano-scale on stem cell behavior are discussed including the mechanotransduction. Biomimetic and bioinspired approaches are highlighted for developing microenvironment of several tissues, and surface engineering applications are discussed in tissue engineering, regenerative medicine and different type of biomaterials in various chapters of the book. This book brings together innovative methodologies and strategies adopted in the research and development of Advanced Surfaces in Stem Cell Research. Well-known worldwide researchers deliberate subjects including: Extracellular matrix proteins for stem cell fate The superficial mechanical and physical properties of matrix microenvironment as stem cell fate regulator Effects of mechanotransduction on stem cell behavior Modulation of stem cells behavior through bioactive surfaces Influence of controlled micro and nanoengineered surfaces on stem cell fate Nanostructured polymeric surfaces for stem cells Laser surface modification techniques and stem cells applications Plasma polymer deposition: a versatile tool for stem cell research Application of bioreactor concept and modeling techniques in bone regeneration and augmentation treatments Substrates and surfaces for control of pluripotent stem cell fate and function Application of biopolymer-based, surface modified devices in transplant medicine and tissue engineering Silk as a natural biopolymer for tissue engineering

Alexey Bezryadin Superconductivity in Nanowires. Fabrication and Quantum Transport Alexey Bezryadin Superconductivity in Nanowires. Fabrication and Quantum Transport
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Alexey Bezryadin Superconductivity in Nanowires. Fabrication and Quantum Transport


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2174.26 руб.

The importance and actuality of nanotechnology is unabated and will be for years to come. A main challenge is to understand the various properties of certain nanostructures, and how to generate structures with specific properties for use in actual applications in Electrical Engineering and Medicine. One of the most important structures are nanowires, in particular superconducting ones. They are highly promising for future electronics, transporting current without resistance and at scales of a few nanometers. To fabricate wires to certain defined standards however, is a major challenge, and so is the investigation and understanding of these properties in the first place. A promising approach is to use carbon nanotubes as well as DNA structures as templates. Many fundamental theoretical questions are still unanswered, e.g. related to the role of quantum fluctuations. This work is tackling them and provides a detailed analysis of the transport properties of such ultrathin wires. It presents an account of theoretical models, charge transport experiments, and also conveys the latest experimental findings regarding fabrication, measurements, and theoretical analysis. In particular, it is the only available resource for the approach of using DNA and carbon nanotubes for nanowire fabrication. It is intended for graduate students and young researchers interested in nanoscale superconductivity. The readers are assumed to have knowledge of the basics of quantum mechanics and superconductivity.

Rickey Yada Nanotechnology and Functional Foods. Effective Delivery of Bioactive Ingredients Rickey Yada Nanotechnology and Functional Foods. Effective Delivery of Bioactive Ingredients
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Rickey Yada Nanotechnology and Functional Foods. Effective Delivery of Bioactive Ingredients


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14994.82 руб.

The continued advancement in the sciences of functional foods and nutraceuticals has clearly established a strong correlation between consumption of bioactives and improved human health and performance. However, the efficacy and bioavailability of these bioactive ingredients (e.g., omega-3 oils, carotenoid antioxidants, vitamins, and probiotic bacteria) in foods often remains a challenge, due to their instability in food products and gastrointestinal tract, as well as their limited bioavailability. In some cases, these bioactive ingredients may impart an undesirable organoleptic characteristic to the final product, which hinders acceptance by consumers. In addressing these challenges, development of effective delivery systems is critical to meet the consumer needs for effective bioactives. The scientific knowledge behind developing effective delivery of bioactive components into modern and wide-ranging food products will be essential to reap their health-promoting benefits and to support the sustained growth of the functional foods market. Nanotechnology and Functional Foods: Effective Delivery of Bioactive Ingredients explores the current data on all aspects of nanoscale packing, carrying and delivery mechanisms of bioactives ingredients to functional foods. The book presents various delivery systems (including nano-emulsions, solid lipid nanoparticles, and polymeric nano-particles), their properties and interactions with other food components, and fate in the human body. Later chapters emphasize the importance of consumers? attitude towards nano-delivery for the success of the technology and investigate the challenges faced by regulatory agencies to control risks and harmonize approaches worldwide. The wide applicability of bioactive delivery systems with the purpose of improving food quality, food safety and human health will make this book a worthy reference for a diverse range of readers in industry, research and academia.

Liwei Lin Design and Fabrication of Self-Powered Micro-Harvesters. Rotating and Vibrated Micro-Power Systems Liwei Lin Design and Fabrication of Self-Powered Micro-Harvesters. Rotating and Vibrated Micro-Power Systems
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Liwei Lin Design and Fabrication of Self-Powered Micro-Harvesters. Rotating and Vibrated Micro-Power Systems


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10873.3 руб.

Presents the latest methods for designing and fabricating self-powered micro-generators and energy harvester systems Design and Fabrication of Self-Powered Micro-Harvesters introduces the latest trends of self-powered generators and energy harvester systems, including the design, analysis and fabrication of micro power systems. Presented in four distinct parts, the authors explore the design and fabrication of: vibration-induced electromagnetic micro-generators; rotary electromagnetic micro-generators; flexible piezo-micro-generator with various widths; and PVDF electrospunpiezo-energy with interdigital electrode. Focusing on the latest developments of self-powered microgenerators such as micro rotary with LTCC and filament winding method, flexible substrate, and piezo fiber-typed microgenerator with sound organization, the fabrication processes involved in MEMS and nanotechnology are introduced chapter by chapter. In addition, analytical solutions are developed for each generator to help the reader to understand the fundamentals of physical phenomena. Fully illustrated throughout and of a high technical specification, it is written in an accessible style to provide an essential reference for industry and academic researchers. Comprehensive treatment of the newer harvesting devices including vibration-induced and rotary electromagnetic microgenerators, polyvinylidene fluoride (PVDF) nanoscale/microscale fiber, and piezo-micro-generators Presents innovative technologies including LTCC (low temperature co-fire ceramic) processes, and PCB (printed circuit board) processes Offers interdisciplinary interest in MEMS/NEMS technologies, green energy applications, bio-related sensors, actuators and generators Presented in a readable style describing the fundamentals, applications and explanations of micro-harvesters, with full illustration


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Covers the fundamental science of grinding and polishing by examining the chemical and mechanical interactions over many scale lengths Manufacturing next generation optics has been, and will continue to be, enablers for enhancing the performance of advanced laser, imaging, and spectroscopy systems. This book reexamines the age-old field of optical fabrication from a materials-science perspective, specifically the multiple, complex interactions between the workpiece (optic), slurry, and lap. It also describes novel characterization and fabrication techniques to improve and better understand the optical fabrication process, ultimately leading to higher quality optics with higher yield. Materials Science and Technology of Optical Fabrication is divided into two major parts. The first part describes the phenomena and corresponding process parameters affecting both the grinding and polishing processes during optical fabrication. It then relates them to the critical resulting properties of the optic (surface quality, surface figure, surface roughness, and material removal rate). The second part of the book covers a number of related topics including: developed forensic tools used to increase yield of optics with respect to surface quality (scratch/dig) and fracture loss; novel characterization and fabrication techniques used to understand/quantify the fundamental phenomena described in the first part of the book; novel and recent optical fabrication processes and their connection with the fundamental interactions; and finally, special techniques utilized to fabricate optics with high damage resistance. Focuses on the fundamentals of grinding and polishing, from a materials science viewpoint, by studying the chemical and mechanical interactions/phenomena over many scale lengths between the workpiece, slurry, and lap Explains how these phenomena affect the major characteristics of the optic workpiece—namely surface figure, surface quality, surface roughness, and material removal rate Describes methods to improve the major characteristics of the workpiece as well as improve process yield, such as through fractography and scratch forensics Covers novel characterization and fabrication techniques used to understand and quantify the fundamental phenomena of various aspects of the workpiece or fabrication process Details novel and recent optical fabrication processes and their connection with the fundamental interactions Materials Science and Technology of Optical Fabrication is an excellent guidebook for process engineers, fabrication engineers, manufacturing engineers, optical scientists, and opticians in the optical fabrication industry. It will also be helpful for students studying material science and applied optics/photonics.
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