The efforts were carried out to study the clinical profile, electrocardiographic profile, to compare the efficacy of ECGs, radiography and cardiac Troponin I and undertake rationale treatment. Anorexia, reduced appetite, weakness, depression, dullness, easy exertion, refractory appetite, ascites, posterior weakness, coughing, dyspnoea, Jugular distension, pulsation, mucus membrane pale, muddy, cyanotic, weight loss, weak femoral pulse/ pulse deficit and syncope were predominant clinical signs of cardiomyopathic dogs. Vertebral heart score (VHS) was more than or equal 8.7 to less than or equal 10.7. On the basis of electrocardiographic features cardiomyopathy were diagnosed as sinus tachycardia (8.69%), sinus arrhythmia (4.34%), right atrial enlargement (4.34%), left atrial enlargement (21.73%), atrial tachycardia (8.69%), atrial fibrillation (17.39%), atrial premature complex (8.69%), left ventricular enlargement (34.78%), ventricular premature complex (13.04%), ventricular tachycardia (8.69%) and sinus arrest (13.04%). In most of cases (95.65%) cardiac Troponin I was found positive (>0.1ng/ml). Cardiac Troponin I is highly sensitive to diagnose the cardiomyopathy.