platelet cd markers by flow cytometry in normal subjects and diabetics

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Litwin Virginia Flow Cytometry in Drug Discovery and Development Litwin Virginia Flow Cytometry in Drug Discovery and Development
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Litwin Virginia Flow Cytometry in Drug Discovery and Development


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10812.96 руб.

This book covers the unique application of flow cytometry in drug discovery and development. The first section includes two introductory chapters, one on flow cytometry and one on biomarkers, as well as a chapter on recent advances in flow cytometry. The second section focuses on the unique challenges and added benefits associated with the use of flow cytometry in the drug development process. The third section contains a single chapter presenting an in depth discussion of validation considerations and regulatory compliance issues associated with drug development.

Mike Leach Practical Flow Cytometry in Haematology Diagnosis Mike Leach Practical Flow Cytometry in Haematology Diagnosis
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Mike Leach Practical Flow Cytometry in Haematology Diagnosis


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11998.84 руб.

The accurate diagnosis of haematologic malignancies is a complex and challenging task. It routinely involves morphologic, molecular, cytogenetic and flow cytometric expertise. To determine what treatment protocol will be followed, it is vital to integrate, interpret and report these results accurately. Flow cytometry is key in this diagnostic pathway. This book guides the reader as to how flow cytometry results should be interpreted and applied to optimize patient care. At the core of this text is an appreciation of clinical, morphological and immunophenotypic correlation and the importance of constant liaison and discussion between the medical and scientific teams. The authors present a logical and practical approach to the diagnosis of blood disorders (both neoplastic and reactive) and evaluate the diagnostic applications of flow cytometry. Practical Flow Cytometry in Haematology Diagnosis provides: • A clinical reference source on all aspects of flow cytometry, covering both malignant and benign conditions • Carefully chosen real-life cases in each chapter, complemented by high quality morphological images • Help in making a diagnosis, together with an understanding of the limitations of the technique and the potential pitfalls All those who instigate, perform, interpret or act upon flow cytometry patient material will find this book an invaluable guide.

Mike Leach Practical Flow Cytometry in Haematology. 100 Worked Examples Mike Leach Practical Flow Cytometry in Haematology. 100 Worked Examples
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Mike Leach Practical Flow Cytometry in Haematology. 100 Worked Examples


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11135.83 руб.

The analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis. This companion text to Practical Flow Cytometry in Haematology Diagnosis contains 100 worked examples drawn from real clinical cases presenting to the authors’ institution. Cases are illustrated with peripheral blood and bone marrow cytology, tissue pathology and cytogenetic and molecular data, which are integrated to generate, where appropriate, a diagnosis based on the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. The spectrum of clinical cases includes adult and paediatric patients, and both neoplastic and reactive disorders. The cases appear in no particular order to challenge the reader to make their own diagnosis. The reader will review May−Grünwald−Giemsa (MGG)-stained films of peripheral blood and bone marrow aspirates presented alongside flow cytometric data and haematoxylin and eosin (H&E)-stained bone marrow and other tissue biopsy sections. Immunohistochemistry is used to further clarify the tissue lineage and cell differentiation. Cytogenetic studies using metaphase preparations are used to identify translocations and chromosome gains and losses whilst interphase fluorescence in situ hybridisation (FISH) studies and polymerase chain reaction (PCR) are used to identify gene fusions, gene rearrangements and deletions. Each case concludes with a discussion of the features that are important to making a diagnosis. The cases are also listed according to disease classification in the appendix so that the text can also be used as a reference. Practical Flow Cytometry in Haematology: 100 Worked Examples: Provides a practical, example-based resource for flow cytometry Demonstrates how flow cytometry results should be interpreted and applied to optimize patient care Includes both malignant and benign conditions Can be used in conjunction with Practical Flow Cytometry in Haematology Diagnosis, by the same author team (ISBN 9780470671207) Practical Flow Cytometry in Haematology: 100 Worked Examples is ideal for practicing haematologists and histopathologists with an interest in haematopathology, but particularly directed at trainee haematologists and scientists preparing for FRCPath and related examinations.

Valery Tuchin V. Advanced Optical Flow Cytometry. Methods and Disease Diagnoses Valery Tuchin V. Advanced Optical Flow Cytometry. Methods and Disease Diagnoses
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Valery Tuchin V. Advanced Optical Flow Cytometry. Methods and Disease Diagnoses


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2174.26 руб.

A detailed look at the latest research in non-invasive in vivo cytometry and its applications, with particular emphasis on novel biophotonic methods, disease diagnosis, and monitoring of disease treatment at single cell level in stationary and flow conditions. This book thus covers the spectrum ranging from fundamental interactions between light, cells, vascular tissue, and cell labeling particles, to strategies and opportunities for preclinical and clinical research. General topics include light scattering by cells, fast video microscopy, polarization, laser-scanning, fluorescence, Raman, multi-photon, photothermal, and photoacoustic methods for cellular diagnostics and monitoring of disease treatment in living organisms. Also presented are discussions of advanced methods and techniques of classical flow cytometry.

Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration
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Satish Totey Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration


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12369.51 руб.

A much-needed primer on the use of laser flow cytometry for stem cell analysis Laser flow cytometry is a powerful tool for rapid analysis of cells for marker expression, cell cycle position, proliferation, and apoptosis. However, no resources specifically address the use of this methodology for the study of stem cells; this is especially important as stem cell analysis involves specialized methods and staining procedures based on specific characteristics such as marker expression, cell size, drug transport, and efflux of the stem cells. Now, this book reviews these procedures, discusses the science behind them, and provides real-world examples to illustrate the usefulness of the methods. It brings together world-class experts in pathology, biophysics, immunology, and stem cell research, who draw upon their extensive experience with the methods and show examples of good data to help guide researchers in the right direction. Chapter coverage includes: Stem cell analysis and sorting using side population Flow cytometry in the study of proliferation and apoptosis Stem cell biology and application Identification and isolation of very small embryonic-like stem cells from murine and human specimens Hematopoietic stem cells—issues in enumeration Human embryonic stem cells: long-term culture and cardiovascular differentiation Limbal stem cells and corneal regeneration Flow cytometric sorting of spermatogonial stem cells Breast cancer stem cells Stem cell marker expression in cells from body cavity fluids This book is an essential resource for all graduate students, practitioners in developing countries, libraries and book repositories of universities and research institutions, and individual researchers. It is also of interest to laboratories engaged in stem cell research and use of stem cells for tissue regeneration, and to any organization dealing in stem cell and tissue regeneration research.

Claudio Ortolani Flow Cytometry of Hematological Malignancies Claudio Ortolani Flow Cytometry of Hematological Malignancies
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Claudio Ortolani Flow Cytometry of Hematological Malignancies


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13344.22 руб.

Flow Cytometry of Hematological Malignancies contains an array of graphical outputs produced by the technique in the study of the most (and the least) common diseases. The images included allow you to compare your own results with a third party reference pattern. There is a detailed description of the main leukocyte antigens, together with a description of their distribution amongst normal and abnormal blood cells. The book also provides a comprehensive description of the phenotype of every neoplastic blood disease recorded in the WHO classification system, including all the instructions needed to recognise and classify even the least common entity. Designed to be practical, the book is perfect for quick consultation and is divided into two main sections. Section I deals with the direct object of immunophenotyping, and Section II deals with the ultimate target of the analysis. More than 50 antigens are covered and every antigen is dealt with in three main parts: general features, cytometric features and practical hints. This authoritative and state-of-the-art reference will be invaluable for clinicians directly involved in the diagnosis and analysis of hematological diseases, including hematologists, hematopathologists, oncologists, pathologists and technicians working in diagnostic laboratories.

Claudio Ortolani Flow Cytometry of Hematological Malignancies Claudio Ortolani Flow Cytometry of Hematological Malignancies
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Claudio Ortolani Flow Cytometry of Hematological Malignancies


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13842.92 руб.

Flow Cytometry of Hematological Malignancies contains an array of graphical outputs produced by the technique in the study of the most (and the least) common diseases. The images included allow you to compare your own results with a third party reference pattern. There is a detailed description of the main leukocyte antigens, together with a description of their distribution amongst normal and abnormal blood cells. The book also provides a comprehensive description of the phenotype of every neoplastic blood disease recorded in the WHO classification system, including all the instructions needed to recognise and classify even the least common entity. Designed to be practical, the book is perfect for quick consultation and is divided into two main sections. Section I deals with the direct object of immunophenotyping, and Section II deals with the ultimate target of the analysis. More than 50 antigens are covered and every antigen is dealt with in three main parts: general features, cytometric features and practical hints. This authoritative and state-of-the-art reference will be invaluable for clinicians directly involved in the diagnosis and analysis of hematological diseases, including hematologists, hematopathologists, oncologists, pathologists and technicians working in diagnostic laboratories.

S. Cahalan Veterinary Embryology S. Cahalan Veterinary Embryology
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S. Cahalan Veterinary Embryology


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9148 руб.

A thorough appreciation of the cellular, molecular and tissue changes which precede the birth of an animal is a fundamental requirement for understanding normal structural development and also abnormal processes which result in congenital defects. This textbook provides information relevant to many subjects taught in preclinical, paraclinical and clinical years. Early chapters describe and explain sequential events relating to the division, growth and differentiation of cells and to the formation of foetal membranes, implantation and placentation. Succeeding chapters trace the origin, growth, development and maturation of the major body systems. Age determination of the embryo and foetus is reviewed in a single chapter. Genetic, chromosomal and environmental factors which adversely affect pre-natal development are reviewed in the final chapter. A reading list at the end of each chapter offers additional sources of information on the topics discussed. Tables, flow diagrams and numerous hand-drawn illustrations provide information in a form which complements the concepts presented in the text. Key features: Written by a team which includes members with expertise in developmental anatomy, molecular biology and clinical aspects of veterinary medicine. The authors have extensive experience in the teaching of veterinary embryology and cognate subjects. Illustrations, hand-drawn by a veterinary graduate, are used extensively to explain organogenesis and system development. An explanatory glossary provides concise information on specialised terms used in the text. The index is designed for easy retrieval of information.

García-Alonso Ángel Platelet Proteomics. Principles, Analysis, and Applications García-Alonso Ángel Platelet Proteomics. Principles, Analysis, and Applications
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García-Alonso Ángel Platelet Proteomics. Principles, Analysis, and Applications


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9019.88 руб.

The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational modifications (PTMs) analysis in platelets. The second part of the book focuses on the main research done so far on platelet proteomics. This includes general proteome mapping by non-gel based separation methods (MudPit), analysis of the general platelet proteome and signaling cascades by gel-based separation methods (2-DE), sub-proteome analyses (secretome/releasate, membrane proteins, organelles). Finally, the last section links the platelet transcriptome and application to disease. This section is highly relevant and includes chapters on proteomics, transcriptomics, functional genomics, systems biology, and their applications to platelet-related diseases.

Abram Dorfman S. Applications of Mathematical Heat Transfer and Fluid Flow Models in Engineering and Medicine Abram Dorfman S. Applications of Mathematical Heat Transfer and Fluid Flow Models in Engineering and Medicine
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Abram Dorfman S. Applications of Mathematical Heat Transfer and Fluid Flow Models in Engineering and Medicine


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8452.19 руб.

Applications of mathematical heat transfer and fluid flow models in engineering and medicine Abram S. Dorfman, University of Michigan, USA Engineering and medical applications of cutting-edge heat and flow models This book presents innovative efficient methods in fluid flow and heat transfer developed and widely used over the last fifty years. The analysis is focused on mathematical models which are an essential part of any research effort as they demonstrate the validity of the results obtained. The universality of mathematics allows consideration of engineering and biological problems from one point of view using similar models. In this book, the current situation of applications of modern mathematical models is outlined in three parts. Part I offers in depth coverage of the applications of contemporary conjugate heat transfer models in various industrial and technological processes, from aerospace and nuclear reactors to drying and food processing. In Part II the theory and application of two recently developed models in fluid flow are considered: the similar conjugate model for simulation of biological systems, including flows in human organs, and applications of the latest developments in turbulence simulation by direct solution of Navier-Stokes equations, including flows around aircraft. Part III proposes fundamentals of laminar and turbulent flows and applied mathematics methods. The discussion is complimented by 365 examples selected from a list of 448 cited papers, 239 exercises and 136 commentaries. Key features: Peristaltic flows in normal and pathologic human organs. Modeling flows around aircraft at high Reynolds numbers. Special mathematical exercises allow the reader to complete expressions derivation following directions from the text. Procedure for preliminary choice between conjugate and common simple methods for particular problem solutions. Criterions of conjugation, definition of semi-conjugate solutions. This book is an ideal reference for graduate and post-graduate students and engineers.

Julia Gaisser Haig Catullus Julia Gaisser Haig Catullus
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Julia Gaisser Haig Catullus


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9953.37 руб.

Catullus is one of the liveliest and most appealing Roman poets. His emotion, charm, and apparent spontaneity resonate with readers as strongly today as in antiquity. This sophisticated literary and historical introduction brings Catullus to life for the modern reader and presents his poetry in all its variety of emotions, subjects, and styles. Places Catullus in a social, historical, and literary context Examines Catallus's style and subjects, and provides a literary introduction to his major themes of love, social life, and politics Discusses the reception of the poems by translators and interpreters

Vinko Jovic Analysis and Modelling of Non-Steady Flow in Pipe and Channel Networks Vinko Jovic Analysis and Modelling of Non-Steady Flow in Pipe and Channel Networks
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Vinko Jovic Analysis and Modelling of Non-Steady Flow in Pipe and Channel Networks


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13198.37 руб.

Analysis and Modelling of Non-Steady Flow in Pipe and Channel Networks deals with flows in pipes and channel networks from the standpoints of hydraulics and modelling techniques and methods. These engineering problems occur in the course of the design and construction of hydroenergy plants, water-supply and other systems. In this book, the author presents his experience in solving these problems from the early 1970s to the present day. During this period new methods of solving hydraulic problems have evolved, due to the development of computers and numerical methods. This book is accompanied by a website which hosts the author's software package, Simpip (an abbreviation of simulation of pipe flow) for solving non-steady pipe flow using the finite element method. The program also covers flows in channels. The book presents the numerical core of the SimpipCore program (written in Fortran). Key features: Presents the theory and practice of modelling different flows in hydraulic networks Takes a systematic approach and addresses the topic from the fundamentals Presents numerical solutions based on finite element analysis Accompanied by a website hosting supporting material including the SimpipCore project as a standalone program Analysis and Modelling of Non-Steady Flow in Pipe and Channel Networks is an ideal reference book for engineers, practitioners and graduate students across engineering disciplines.

Gaiman Neil The Graveyard Book Gaiman Neil The Graveyard Book
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Gaiman Neil The Graveyard Book


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1172 руб.

Nobody Owens, known to his friends as Bod, is a normal boy. He would be completely normal if he didn't live in a graveyard, being raised and educated by ghosts. There are dangers and adventures for Bod in the graveyard. But it is in the land of the living that real danger lurks for it is there that the man Jack lives and he has already killed Bod's family. A deliciously dark masterwork by bestselling author Neil Gaiman, with illustrations by award-winning Chris Riddell.

Mikhail Panfilov Physicochemical Fluid Dynamics in Porous Media. Applications in Geosciences and Petroleum Engineering Mikhail Panfilov Physicochemical Fluid Dynamics in Porous Media. Applications in Geosciences and Petroleum Engineering
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Mikhail Panfilov Physicochemical Fluid Dynamics in Porous Media. Applications in Geosciences and Petroleum Engineering


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9801.68 руб.

A unique and timely book on understanding and tailoring the flow of fluids in porous materials Porous media play a key role in chemical processes, gas and water purification, gas storage and the development of new multifunctional materials. Understanding hydrodynamics in porous media is decisive for enabling a wide range of applications in materials science and chemical engineering. This all-encompassing book offers a timely overview of all flow and transport processes in which chemical or physicochemical phenomena such as dissolution, phase transition, reactions, adsorption, diffusion, capillarity, and surface phenomena are essential. It brings together both theoretical and experimental results and includes important industrial applications. Physicochemical Fluid Dynamics in Porous Media: Applications in Geoscience and Petroleum Engineering explains the thermodynamics of phase equilibria for multicomponent fluids, physicochemical models of single-phase and immiscible two-phase flow, based on the macroscopic theory of oil displacement by water. It also covers the theory of two-phase flow with partial miscibility and describes partially miscible flows with phase transitions by means of the negative saturation approach. The final chapters are devoted to flow with chemical reactions, based on the example of in-situ leaching of uranium, and flow with bio-chemical reactions in terms of the underground storage of hydrogen. -Brings together the theoretical and experimental results necessary for the understanding of hydrodynamics in porous media -Covers important industrial applications such as underground leaching of uranium and underground storage of hydrogen -Presents a state-of-the-art overview and summarizes the research results usually found only scattered in the literature Physicochemical Fluid Dynamics in Porous Media: Applications in Geoscience and Petroleum Engineering will appeal to chemical engineers, materials scientists, applied physicists, and mechanical engineers.

Adams William Henry Davenport By-ways in Book-land: Short Essays on Literary Subjects Adams William Henry Davenport By-ways in Book-land: Short Essays on Literary Subjects
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Adams William Henry Davenport By-ways in Book-land: Short Essays on Literary Subjects


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0 руб.

Misha Gorfunkle Mechanics of Fluid Flow Misha Gorfunkle Mechanics of Fluid Flow
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Misha Gorfunkle Mechanics of Fluid Flow


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15897.66 руб.

The mechanics of fluid flow is a fundamental engineering discipline explaining both natural phenomena and human-induced processes, and a thorough understanding of it is central to the operations of the oil and gas industry. This book, written by some of the world’s best-known and respected petroleum engineers, covers the concepts, theories, and applications of the mechanics of fluid flow for the veteran engineer working in the field and the student, alike. It is a must-have for any engineer working in the oil and gas industry.

Jarecki Alfred Atlas of Comparative Diagnostic and Experimental Hematology Jarecki Alfred Atlas of Comparative Diagnostic and Experimental Hematology
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Jarecki Alfred Atlas of Comparative Diagnostic and Experimental Hematology


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8945.33 руб.

A vital resource on blood and bone marrow cell morphology in laboratory animal medicine. This fully revised new edition is an essential reference for clinical pathologists in diagnostic laboratories, and medical or veterinary research. The atlas contains over 400 color images of cells from the peripheral blood and bone marrow from a variety of animals encountered in laboratory animal medicine, in health and disease. Key features: New chapter on flow cytometry and its application in terms of routine analyses as a means of identifying abnormalities in cell marker expression, which is of particular relevance for pre-clinical safety assessment Covers the most recent developments in laboratory animal hematology, including parameters measured by the latest generation of analyzers Coverage of a wide range of laboratory animal species, as well as those used in clinical veterinary trials Photomicrographs present normal and abnormal blood cells from a variety of hematological conditions along with descriptive text

Joseph Choukroun Platelet Rich Fibrin in Regenerative Dentistry. Biological Background and Clinical Indications Joseph Choukroun Platelet Rich Fibrin in Regenerative Dentistry. Biological Background and Clinical Indications
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Joseph Choukroun Platelet Rich Fibrin in Regenerative Dentistry. Biological Background and Clinical Indications


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9373.54 руб.

The first book devoted exclusively to the subject, Platelet Rich Fibrin in Regenerative Dentistry offers comprehensive, evidence-based coverage of the biological basis and clinical applications of PRF in dentistry. Co-edited by a leading researcher in tissue regeneration and the inventor of the PRF technique, it brings together original contributions from expert international researchers and clinicians. Chapters cover the biological foundation of PRF before addressing specific uses of the technology within clinical dentistry. Topics describe the use of PRF in many dental applications, including extraction socket management, sinus lifting procedures, root coverage, periodontal regeneration, soft tissue healing around implants, guided bone regeneration, and facial esthetics. The text is supplemented with color photographs and explanatory illustrations throughout. Platelet Rich Fibrin in Regenerative Dentistry: Biological Background and Clinical Indications is an indispensable professional resource for periodontists, oral surgeons and oral and maxillofacial surgeons, as well as general dentists who use PRF or are interested in introducing it into their practices. It is also an excellent reference for undergraduate and postgraduate dental students.

Alain Boutier Laser Velocimetry in Fluid Mechanics Alain Boutier Laser Velocimetry in Fluid Mechanics
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Alain Boutier Laser Velocimetry in Fluid Mechanics


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14546.93 руб.

In fluid mechanics, velocity measurement is fundamental in order to improve the behavior knowledge of the flow. Velocity maps help us to understand the mean flow structure and its fluctuations, in order to further validate codes. Laser velocimetry is an optical technique for velocity measurements; it is based on light scattering by tiny particles assumed to follow the flow, which allows the local fluid flow velocity and its fluctuations to be determined. It is a widely used non-intrusive technique to measure velocities in fluid flows, either locally or in a map. This book presents the various techniques of laser velocimetry, as well as their specific qualities: local measurements or in plane maps, mean or instantaneous values, 3D measurements. Flow seeding with particles is described with currently used products, as well as the appropriate aerosol generators. Post-processing of data allows us to extract synthetic information from measurements and to perform comparisons with results issued from CFD codes. The principles and characteristics of the different available techniques, all based on the scattering of light by tiny particles embedded in the flow, are described in detail; showing how they deliver different information, either locally or in a map, mean values and turbulence characteristics.

Stepan Podzimek Light Scattering, Size Exclusion Chromatography and Asymmetric Flow Field Flow Fractionation. Powerful Tools for the Characterization of Polymers, Proteins and Nanoparticles Stepan Podzimek Light Scattering, Size Exclusion Chromatography and Asymmetric Flow Field Flow Fractionation. Powerful Tools for the Characterization of Polymers, Proteins and Nanoparticles
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Stepan Podzimek Light Scattering, Size Exclusion Chromatography and Asymmetric Flow Field Flow Fractionation. Powerful Tools for the Characterization of Polymers, Proteins and Nanoparticles


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9490.51 руб.

A comprehensive, practical approach to three powerful methods of polymer analysis and characterization This book serves as a complete compendium of three important methods widely used for the characterization of synthetic and natural polymers—light scattering, size exclusion chromatography (SEC), and asymmetric flow field flow fractionation (A4F). Featuring numerous up-to-date examples of experimental results obtained by light scattering, SEC, and A4F measurements, Light Scattering, Size Exclusion Chromatography and Asymmetric Flow Field Flow Fractionation takes an all-in-one approach to deliver a complete and thorough explanation of the principles, theories, and instrumentation needed to characterize polymers from the viewpoint of their molar mass distribution, size, branching, and aggregation. This comprehensive resource: Is the only book gathering light scattering, size exclusion chromatography, and asymmetric flow field flow fractionation into a single text Systematically compares results of size exclusion chromatography with results of asymmetric flow field flow fractionation, and how these two methods complement each other Provides in-depth guidelines for reproducible and correct determination of molar mass and molecular size of polymers using SEC or A4F coupled with a multi-angle light scattering detector Offers a detailed overview of the methodology, detection, and characterization of polymer branching Light Scattering, Size Exclusion Chromatography and Asymmetric Flow Field Flow Fractionation should be of great interest to all those engaged in the polymer analysis and characterization in industrial and university research, as well as in manufacturing quality control laboratories. Both beginners and experienced can confidently rely on this volume to confirm their own understanding or to help interpret their results.

Вероника Ларссон Not frigid in bed with a man. Lessons of sex. The best in bed, how to become… Вероника Ларссон Not frigid in bed with a man. Lessons of sex. The best in bed, how to become…
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Вероника Ларссон Not frigid in bed with a man. Lessons of sex. The best in bed, how to become…


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196 руб.

Important and useful manual for the female. Secrets for women. How to become a good mistress? This guide is written by a girl with great experience in sex and good taste in intimate relationships. Subjects of the manual: fantasy, passion, sexy underwear, games, initiative, physical preparation. From “modest” to “tigress”.

John Cotter Advances in Fisheries Science. 50 Years on From Beverton and Holt John Cotter Advances in Fisheries Science. 50 Years on From Beverton and Holt
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John Cotter Advances in Fisheries Science. 50 Years on From Beverton and Holt


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20542.81 руб.

This timely book brings readers up to date on the wide range of advances made in fisheries science since the publication in 1957 of On the Dynamics of Exploited Fish Populations (Beverton and Holt), regarded by many fisheries scientists as one of the most important books on fisheries yet published. Traditional fishery subjects covered include historic declines and changes in fishing fleets, fisheries management and stock assessments, data-poor situations, simulation and modelling of fished stocks, fisheries economics, assessing reproductive potential and dispersal of larvae, fisheries for sharks and rays, and use of marine technology. Additionally, related subjects of increasing importance now that ecological approaches to management are coming to the fore are presented. They include benthic ecology, ecosystem changes linked to fishing, life history theory, the effects of chemicals on fish reproduction, and use of sounds in the sea by marine life. Several chapters offer stimulating philosophical discussion of the many controversial areas still existing. This significant book, edited by Andy Payne, John Cotter and Ted Potter and containing contributions by world-renowned fisheries scientists, including many based at Cefas (where Beverton and Holt's original work was carried out) is an essential purchase for fisheries managers and scientists, fish biologists, marine scientists and ecologists. Libraries in all universities and research establishments where fisheries and biological sciences are studied and taught are likely to need copies of this landmark publication.

Baojiang Sun Multiphase Flow in Oil and Gas Well Drilling Baojiang Sun Multiphase Flow in Oil and Gas Well Drilling
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Baojiang Sun Multiphase Flow in Oil and Gas Well Drilling


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10498.36 руб.

A major contribution to the state-of-the-art for those interested in multiphase flow in well-bore, drilling cutting, hydrate and/or acid gas involvements The author is a leading researcher on the topics presented, and his development of gas-liquid flow pattern transition mechanism and multiphase flow models are major contributions to the multi-phase flow in wellbore Focuses on acid gas and hydrate involvements, offering the latest results from drilling engineering computation research Presents an emerging hot spot in petroleum engineering, with more multi-phase flow methodologies developed and adopted to improve the engineering process for gas & oil drilling and production

Joe Depner S. Hydrodynamics of Time-Periodic Groundwater Flow. Diffusion Waves in Porous Media Joe Depner S. Hydrodynamics of Time-Periodic Groundwater Flow. Diffusion Waves in Porous Media
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Joe Depner S. Hydrodynamics of Time-Periodic Groundwater Flow. Diffusion Waves in Porous Media


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12745.17 руб.

Hydrodynamics of Time-Periodic Groundwater Flow introduces the emerging topic of periodic fluctuations in groundwater. While classical hydrology has often focused on steady flow conditions, many systems display periodic behavior due to tidal, seasonal, annual, and human influences. Describing and quantifying subsurface hydraulic responses to these influences may be challenging to those who are unfamiliar with periodically forced groundwater systems. The goal of this volume is to present a clear and accessible mathematical introduction to the basic and advanced theory of time-periodic groundwater flow, which is essential for developing a comprehensive knowledge of groundwater hydraulics and groundwater hydrology. Volume highlights include: Overview of time-periodic forcing of groundwater systems Definition of the Boundary Value Problem for harmonic systems in space and time Examples of 1-, 2-, and 3-dimensional flow in various media Attenuation, delay, and gradients, stationary points and flow stagnation Wave propagation and energy transport Hydrodynamics of Time-Periodic Groundwater Flow presents numerous examples and exercises to reinforce the essential elements of the theoretical development, and thus is eminently well suited for self-directed study by undergraduate and graduate students. This volume will be a valuable resource for professionals in Earth and environmental sciences who develop groundwater models., including in the fields of groundwater hydrology, soil physics, hydrogeology, geoscience, geophysics, and geochemistry. Time-periodic phenomena are also encountered in fields other than groundwater flow, such as electronics, heat transport, and chemical diffusion. Thus, students and professionals in the field of chemistry, electronic engineering, and physics will also find this book useful.


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The analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis. This companion text to Practical Flow Cytometry in Haematology Diagnosis contains 100 worked examples drawn from real clinical cases presenting to the authors’ institution. Cases are illustrated with peripheral blood and bone marrow cytology, tissue pathology and cytogenetic and molecular data, which are integrated to generate, where appropriate, a diagnosis based on the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. The spectrum of clinical cases includes adult and paediatric patients, and both neoplastic and reactive disorders. The cases appear in no particular order to challenge the reader to make their own diagnosis. The reader will review May−Grünwald−Giemsa (MGG)-stained films of peripheral blood and bone marrow aspirates presented alongside flow cytometric data and haematoxylin and eosin (H&E)-stained bone marrow and other tissue biopsy sections. Immunohistochemistry is used to further clarify the tissue lineage and cell differentiation. Cytogenetic studies using metaphase preparations are used to identify translocations and chromosome gains and losses whilst interphase fluorescence in situ hybridisation (FISH) studies and polymerase chain reaction (PCR) are used to identify gene fusions, gene rearrangements and deletions. Each case concludes with a discussion of the features that are important to making a diagnosis. The cases are also listed according to disease classification in the appendix so that the text can also be used as a reference. Practical Flow Cytometry in Haematology: 100 Worked Examples: Provides a practical, example-based resource for flow cytometry Demonstrates how flow cytometry results should be interpreted and applied to optimize patient care Includes both malignant and benign conditions Can be used in conjunction with Practical Flow Cytometry in Haematology Diagnosis, by the same author team (ISBN 9780470671207) Practical Flow Cytometry in Haematology: 100 Worked Examples is ideal for practicing haematologists and histopathologists with an interest in haematopathology, but particularly directed at trainee haematologists and scientists preparing for FRCPath and related examinations.
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